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Urea,_N-[3-[5-[_4-fluorophenyl_methyl]-2-thienyl]-1-methyl-2-propyn-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) ADC Linker (3) Adrenergic Receptor (1) Amino Acid Derivatives (7) Apoptosis (3) Autophagy (1) Bacterial (4) Bcl-2 Family (1) Biochemical Assay Reagents (12) Carbonic Anhydrase (2) Ceramidase (1) Collagen (1) Drug Derivative (8) Drug Intermediate (7) Drug Isomer (3) Drug Metabolite (1) Endogenous Metabolite (5) Endothelin Receptor (1) Environmental Pollutants (4) Epoxide Hydrolase (1) ERK (2) Interleukin Related (2) Isotope-Labeled Compounds (12) Mas-related G-protein-coupled Receptor (MRGPR) (2) MMP (1) MOFs (17) Nucleoside Antimetabolite/Analog (4) PSMA (4) Radionuclide-Drug Conjugates (RDCs) (3) Reference Standards (13) β-catenin (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (5) Infection (5) Inflammation/Immunology (2) Metabolic Disease (5) Neurological Disease (6)
Click Chemistry:	ADC Synthesis (1) Alkynes (4)
Oligonucleotides:	Adenosine (1) Guanosine (1) Nucleoside Analogs (4) Uridine (1)

100

Inhibitors & Agonists

Screening-Bibliotheken

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Art. -Nr.	Produktname	Target	Forschungsgebiete	Chemical Structure

HY-Y0271

*Urea* Maximum Cited Publications 6 Publications Verification Carbonyl diamide	Environmental Pollutants Apoptosis Endogenous Metabolite Carbonic Anhydrase ERK	Cardiovascular Disease Cancer
Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-W011688

Methyl palmitoleate 1 Publications Verification (Z)-methyl hexadec-9-enoate; methyl cis-9-Hexadecenoate	Drug Isomer	Others
Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties .

HY-B1158

Imidazolidinyl urea	Environmental Pollutants Mas-related G-protein-coupled Receptor (MRGPR) Interleukin Related Bacterial	Infection
Imidazolidinyl urea is a commonly used antibacterial preservative in cosmetics and pharmaceuticals that releases formaldehyde through decomposition. Imidazolidinyl urea can also be used in the preparation of multifunctional hydrogels for the care of infectious wounds. Imidazolidinyl urea has broad-spectrum antibacterial activity, which mainly inhibits the reproduction of gram-negative bacteria and gram-positive bacteria, and restricts the growth of yeast and mold to a certain extent. Imidazolidinyl urea can induce non-histaminergic allergy by MRGPRX2 activation of mast cells .

HY-W028185

*3-(4-Fluorophenyl)propanoic acid*	Biochemical Assay Reagents	Others
3-(4-Fluorophenyl)propanoic acid is a biochemical reagent and pharmaceutical intermediate used in life science-related research.

HY-118877

Urea-13C 1 Publications Verification Carbonyl diamide-¹³C	Isotope-Labeled Compounds	Infection
Urea- ¹³C is the ¹³C labelled urea. The Urea- ¹³C breath test ( ¹³C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection .

HY-147287

*Glu-urea-Glu-NHS ester*	PSMA Drug Intermediate	Cancer
Glu-urea-Glu-NHS ester is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu. Glu-urea-Glu-NHS ester can be used for synthesis of small-molecule prostate-specific membrane antigen (PSMA) inhibitors, imaging agents (such as PSMAi-PEG conjugates), and targeted drug delivery vehicles .

HY-W009082

Methyl behenate 1 Publications Verification methyl docosanoate	Biochemical Assay Reagents	Others
Methyl behenate (Methyl docosanoate) is a fatty acid methyl ester, can be found in the plant Aspidopterys obcordata Lemsl. Methyl behenate can be used as a phase change material .

HY-W004286

Methyl laurate methyl dodecanoate	Environmental Pollutants Drug Derivative	Others
Methyl laurate (Methyl dodecanoate) is a fatty acid methyl ester. Methyl laurate can serve as a raw material to produce sucrose monolaurate via transesterification with sucrose .

HY-Y0271S1

Urea-d4 Carbonyl diamide-d₄	Endogenous Metabolite	Others
Urea-d₄ is the deuterium labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-W281186

*2-Chloro-N-(2,3-dihydro-1,1-dioxido-3-thienyl)acetamide*	Drug Intermediate	Others
2-Chloro-N-(2,3-dihydro-1,1-dioxido-3-thienyl)acetamide is a pharmaceutical intermediate.

HY-152684

*2′-O-2-Propyn-1-ylguanosine*	Nucleoside Antimetabolite/Analog	Others
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W011002

*Fmoc-3-Ala(2-thienyl)-OH*	Amino Acid Derivatives	Others
Fmoc-3-Ala(2-thienyl)-OH is an alanine derivative .

HY-W016032

*Fmoc-3-Ala(3-thienyl)-OH*	Amino Acid Derivatives	Others
Fmoc-3-Ala(3-thienyl)-OH is an alanine derivative .

HY-P5290

HYNIC-PSMA	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as ¹⁸⁸Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research . HYNIC-PSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-109617

*4-(4-Fluorophenyl)benzoic acid*	Bcl-2 Family	Cancer
4-(4-Fluorophenyl)benzoic acid (Compoud 6) can bind to Bcl-2 with a K_D value of 400 μM. 4-(4-Fluorophenyl)benzoic acid can be used to develope Bcl-2 selective anti-cancer agent .

HY-I0182

*2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl) methyl]thiophene*	Drug Intermediate	Others
2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl) methyl]thiophene is a drug intermediate for synthesis of various active compounds.

HY-I0393

*3-(2-Thienyl)-L-alanine* L-3-(2-thienyl)alanine	Amino Acid Derivatives	Others
3-(2-Thienyl)-L-alanine is an alanine derivative .

HY-W009350

Diazolidinyl urea	Environmental Pollutants Bacterial	Infection
Diazolidinyl urea is a broad-spectrum preservative commonly used in cosmetics. Diazolidinyl urea exerts antibacterial effects by decomposing and releasing formaldehyde. Diazolidinyl urea is effective against most contaminating microorganisms, especially Pseudomonas .

HY-W209628

Methyl 2-acetoxybenzoate methyl acetylsalicylate	Drug Intermediate	Inflammation/Immunology
Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) is a safe and simple anti-inflammatory aspirin prodrug. Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) can be chemical or enzymatically hydrolysed to methyl 2-hydroxy benzoate. Methyl 2-acetoxybenzoate (Methyl acetylsalicylate) can be used as analgesic agent in liniments and also inflammatory diseases research .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .

HY-Y0271R

Urea (Standard) Carbonyl diamide (Standard)	Carbonic Anhydrase Reference Standards Endogenous Metabolite ERK Apoptosis	Cardiovascular Disease Cancer
Urea (Standard) is the analytical standard of Urea. This product is intended for research and analytical applications. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-P5292A

HYNIC-iPSMA TFA	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity . HYNIC-iPSMA TFA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-113972

Methyl mycophenolate	Others	Inflammation/Immunology
Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae .

HY-N8064

Methyl cis-15-tetracosenoate methyl nervonate; methyl (Z)-tetracos-15-enoate; Nervonic acid methyl este	Drug Derivative	Neurological Disease
Methyl cis-15-tetracosenoate (Methyl nervonate; Methyl (Z)-tetracos-15-enoate; Nervonic acid methyl ester) is the methyl ester form of nervonic acid (Nervonic acid, HY-N2526). Nervonic acid is an orally active monounsaturated fatty acid. Nervonic acid exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. Nervonic acid can be used in the research of neurodegenerative diseases .

HY-23337S

*1-Methyl-3-((tetrahydrofuran-3-yl)methyl)urea-d3*	Isotope-Labeled Compounds	Others
1-Methyl-3-((tetrahydrofuran-3-yl)methyl)urea-d₃ is the deuterium labeled γ-Tocotrienol. γ-Tocotrienol is an active form of vitamin E[1].

HY-W029719

*[5-(2-Thienyl)-3-isoxazolyl]methanol*	Bacterial	Infection
[5-(2-Thienyl)-3-isoxazolyl]methanol (Compound D) is an AgrA-DNA binding inhibitor. [5-(2-Thienyl)-3-isoxazolyl]methanol can be used for S.aureus infection research .

HY-W141842

*3-(2-Thienyl)-DL-alanine*	Amino Acid Derivatives	Others
3-(2-Thienyl)-DL-alanine is an alanine derivative .

HY-154338

*N-Benzoyl-2′-O-2-propyn-1-yladenosine*	Nucleoside Antimetabolite/Analog	Cancer
N-Benzoyl-2′-O-2-propyn-1-yladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) . N-Benzoyl-2′-O-2-propyn-1-yladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135795

1-Cyclohexyl-3-dodecyl urea CDU; N-Cyclohexyl-N-dodecyl Urea; NCND	Epoxide Hydrolase	Cardiovascular Disease Metabolic Disease
1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor. 1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) increases epoxyeicosatrienoic acids (EETs) levels and lowers blood pressure in angiotensin II (Ang II) hypertension .

HY-131964

Imidacloprid-urea	Drug Metabolite	Others
Imidacloprid-urea is a metabolite of Imidacloprid (HY-B0838). Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton. Imidacloprid-urea can occupy or block adsorption sites of imidacloprid on soil, potentially affecting the fate, transport, and bioavailability of imidacloprid in the environment .

HY-154733

*9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine*	Nucleoside Antimetabolite/Analog	Cancer
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P5292

HYNIC-iPSMA	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
HYNIC-iPSMA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA has excellent specificity and sensitivity . HYNIC-iPSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-128930

*6-O-2-Propyn-1-yl-D-galactose*	ADC Linker	Cancer
6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic agents and applications in antibody-agent conjugation. 6-O-2-Propyn-1-yl-D-galactose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-108379

*Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid*	ADC Linker	Cancer
Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W016474A

*1-(4-Fluorophenyl)piperazine hydrochloride* 1-(4-fluorophenyl)piperazinediium hydrochloride	Drug Derivative	Neurological Disease
1-(4-Fluorophenyl)piperazine (1-(4-Fluorophenyl)piperazinediium) hydrochloride is a substituted phenylpiperazine .

HY-139062

*C6 Urea* Ceramide** C6 Ceramide (d18:1/6:0) Urea; Cer(d18:1/6:0) Urea; D-erythro-Urea-C6-Ceramide	Apoptosis Ceramidase Autophagy β-catenin	Cancer
C6 Urea Ceramide (Cer(d18:1/6:0) Urea) is an inhibitor of neutral ceramidase. C6 Urea Ceramide increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and HT-29 colon cancer cells. C6 Urea Ceramide (5-10 μM) inhibits proliferation of HT-29 cells and induces apoptosis and autophagy, but is not toxic to non-cancerous cells. C6 Urea Ceramide decreases total and phosphorylated β-catenin levels in HT-29 and HCT116 cells, and induces colocalization of β-catenin with the 20S proteasome. C6 Urea Ceramide (1.25, 2.5, and 5 mg/kg) reduced tumor growth and increased C16, C18, C20, and C24 ceramide levels in tumor tissues in the HT-29 mouse xenograft model.

HY-W009082R

Methyl behenate (Standard) methyl docosanoate (Standard)	Reference Standards Biochemical Assay Reagents	Others
Methyl behenate (Standard) is the analytical standard of Methyl behenate (HY-W009082). This product is intended for research and analytical applications. Methyl behenate (Methyl docosanoate) is a fatty acid methyl ester. Methyl behenate can be isolated from the plant Aspidopterys obcordata Lemsl. Methyl behenate can be used as a phase change material .

HY-77160

Ethyl 3-(4-fluorophenyl)-3-oxopropanoate	Biochemical Assay Reagents	Others
Ethyl 3-(4-fluorophenyl)-3-oxopropanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W011857R

*3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid (Standard)*	Reference Standards
3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid (Standard) is the analytical standard of 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid. This product is intended for research and analytical applications.

HY-W699637

*4-[[(4-Fluorophenyl)imino]methyl]phenol-d4* 4-{(E)-[(4-fluorophenyl)imino]methyl}phenol-d₄	Isotope-Labeled Compounds	Others
4-[[(4-Fluorophenyl)imino]methyl]phenol-d₄ (4-{(E)-[(4-Fluorophenyl)imino]methyl}phenol-d₄) is the deuterium labeled 4-[[(4-Fluorophenyl)imino]methyl]phenol (HY-W014178).

HY-W751537

*4-[[(4-Fluorophenyl)imino]methyl]phenol-13C6* 4-{(E)-[(4-fluorophenyl)imino]methyl}phenol-¹³C₆	Isotope-Labeled Compounds	Others
4-[[(4-Fluorophenyl)imino]methyl]phenol- ¹³C₆ (4-{(E)-[(4-Fluorophenyl)imino]methyl}phenol- ¹³C₆) is the ¹³C-labeled 4-[[(4-Fluorophenyl)imino]methyl]phenol (HY-W014178).

HY-W714523

*1-Bis(4-fluorophenyl)methyl* Piperazine-d8**	Isotope-Labeled Compounds	Others
1-Bis(4-fluorophenyl)methyl Piperazine-d₈ is the deuterium labeled 1-(Bis(4-fluorophenyl)methyl)piperazine (HY-W009293).

HY-I0423

*3-(2-Thienyl)-D-alanine* D-3-(2-thienyl)alanine	Amino Acid Derivatives	Others
3-(2-Thienyl)-D-alanine is an alanine derivative .

HY-W009293S

*1-(Bis(4-fluorophenyl)methyl)piperazine-d4* N-(4,4-Difluorobenzhydryl)piperazine-d₄	Isotope-Labeled Compounds	Others
1-(Bis(4-fluorophenyl)methyl)piperazine-d₄ (N-(4,4-Difluorobenzhydryl)piperazine-d₄) is the deuterium labeled 1-(Bis(4-fluorophenyl)methyl)piperazine.

HY-152580

*5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine*	Nucleoside Antimetabolite/Analog	Others
5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W350212

*2-Propyn-1-yl α-D-galactopyranoside*	Biochemical Assay Reagents	Others
2-Propyn-1-yl α-D-galactopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-B1158R

*Imidazolidinyl urea* (Standard)**	Reference Standards Bacterial Mas-related G-protein-coupled Receptor (MRGPR) Interleukin Related	Infection
Imidazolidinyl urea (Standard) is the analytical standard of Imidazolidinyl urea. This product is intended for research and analytical applications. Imidazolidinyl urea is a commonly used antibacterial preservative in cosmetics and pharmaceuticals that releases formaldehyde through decomposition. Imidazolidinyl urea can also be used in the preparation of multifunctional hydrogels for the care of infectious wounds. Imidazolidinyl urea has broad-spectrum antibacterial activity, which mainly inhibits the reproduction of gram-negative bacteria and gram-positive bacteria, and restricts the growth of yeast and mold to a certain extent. Imidazolidinyl urea can induce non-histaminergic allergy by MRGPRX2 activation of mast cells .

HY-Z3151

*3'-(2-Fluorophenyl) ezetimibe*	Drug Isomer	Cardiovascular Disease
3'-(2-Fluorophenyl) ezetimibe is an isomer of the cholesterol transport inhibitor Ezetimibe (HY-17376).

HY-W039896

Propargyl a-D-mannopyranoside α-D-Mannopyranoside, 2-propyn-1-yl	Biochemical Assay Reagents
Propargyl A-D-Mannopyranoside (α-D-Mannopyranoside, 2-propyn-1-yl) is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .

Art. -Nr.	Produktname

HY-L203

Methylation Compound Library

342 compounds

Methylation is an epigenetic modification mechanism that involves adding methyl groups to molecules such as DNA and histones, which can alter gene expression without changing the DNA sequence. This process is catalyzed by enzymes such as DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs), and can be reversed by demethylases. The balance of methylation and demethylation is crucial for maintaining cellular function and genomic stability. Abnormal regulation of methylation may lead to a variety of diseases, including cancer, neurological disorders, and developmental abnormalities. A deep understanding of the molecular mechanisms of methylation metabolism is essential for developing therapeutic strategies for diseases associated with methylation dysregulation.

MCE contains 342 compounds targeting methylation/demethylation enzymes, which is of significant value for studying the pathways of methylation metabolism and exploring their mechanisms of action in diseases.

Art. -Nr.	Produktname	Type

HY-W028185

*3-(4-Fluorophenyl)propanoic acid*	Biochemical Assay Reagents
3-(4-Fluorophenyl)propanoic acid is a biochemical reagent and pharmaceutical intermediate used in life science-related research.

HY-N8064

Methyl cis-15-tetracosenoate

methyl nervonate; methyl (Z)-tetracos-15-enoate; Nervonic acid methyl este

Biochemical Assay Reagents

Methyl cis-15-tetracosenoate (Methyl nervonate; Methyl (Z)-tetracos-15-enoate; Nervonic acid methyl ester) is the methyl ester form of nervonic acid (Nervonic acid, HY-N2526). Nervonic acid is an orally active monounsaturated fatty acid. Nervonic acid exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. Nervonic acid can be used in the research of neurodegenerative diseases .

HY-77160

Ethyl 3-(4-fluorophenyl)-3-oxopropanoate	Biochemical Assay Reagents
Ethyl 3-(4-fluorophenyl)-3-oxopropanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W350212

2-Propyn-1-yl α-D-galactopyranoside

Biochemical Assay Reagents

2-Propyn-1-yl α-D-galactopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W039896

Propargyl a-D-mannopyranoside

α-D-Mannopyranoside, 2-propyn-1-yl

Biochemical Assay Reagents

Propargyl A-D-Mannopyranoside (α-D-Mannopyranoside, 2-propyn-1-yl) is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .

HY-W009543

*2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane* 2-(3-Chloropropyl)-2-(p-fluorophenyl)-1,3-dioxolane	Biochemical Assay Reagents
2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane (2-(3-Chloropropyl)-2-(p-fluorophenyl)-1,3-dioxolane) is a kind of biological materials or organic compounds that are widely used in life science research.

Art. -Nr.	Produktname	Target	Research Area

HY-W011002

*Fmoc-3-Ala(2-thienyl)-OH*	Amino Acid Derivatives	Others
Fmoc-3-Ala(2-thienyl)-OH is an alanine derivative .

HY-W016032

*Fmoc-3-Ala(3-thienyl)-OH*	Amino Acid Derivatives	Others
Fmoc-3-Ala(3-thienyl)-OH is an alanine derivative .

HY-P5290

HYNIC-PSMA	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as ¹⁸⁸Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research . HYNIC-PSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-I0393

*3-(2-Thienyl)-L-alanine* L-3-(2-thienyl)alanine	Amino Acid Derivatives	Others
3-(2-Thienyl)-L-alanine is an alanine derivative .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .

HY-P5292A

HYNIC-iPSMA TFA	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity . HYNIC-iPSMA TFA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-W141842

*3-(2-Thienyl)-DL-alanine*	Amino Acid Derivatives	Others
3-(2-Thienyl)-DL-alanine is an alanine derivative .

HY-P5292

HYNIC-iPSMA	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
HYNIC-iPSMA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA has excellent specificity and sensitivity . HYNIC-iPSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-I0423

*3-(2-Thienyl)-D-alanine* D-3-(2-thienyl)alanine	Amino Acid Derivatives	Others
3-(2-Thienyl)-D-alanine is an alanine derivative .

HY-78746A

*(3S,4R,5S)-rel-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxylic acid*	Amino Acid Derivatives	Others
D-Proline, 3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-, (3S,4R,5S)-rel- is a proline derivative .

Art. -Nr.	Produktname	Category	Target	Chemical Structure

HY-Y0271

*Urea* Maximum Cited Publications 6 Publications Verification Carbonyl diamide	Structural Classification Natürliche Produkte Microorganisms Classification of Application Fields Endogenous metabolite Disease Research Fields Biological Pesticide Research Source Classification Cancer Agricultural Research	Environmental Pollutants Apoptosis Endogenous Metabolite Carbonic Anhydrase ERK
Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-W011688

Methyl palmitoleate 1 Publications Verification (Z)-methyl hexadec-9-enoate; methyl cis-9-Hexadecenoate	Structural Classification other families Classification of Application Fields Other Diseases Plants Disease Research Fields Lipid Source Classification	Drug Isomer
Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties .

HY-W009082

Methyl behenate 1 Publications Verification methyl docosanoate	Structural Classification Natürliche Produkte other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Biochemical Assay Reagents
Methyl behenate (Methyl docosanoate) is a fatty acid methyl ester, can be found in the plant Aspidopterys obcordata Lemsl. Methyl behenate can be used as a phase change material .

HY-W004286

Methyl laurate methyl dodecanoate	Structural Classification Natürliche Produkte Classification of Application Fields Labiatae Other Diseases Plants Medicago truncatula Gaertn. Disease Research Fields Source Classification	Environmental Pollutants Drug Derivative
Methyl laurate (Methyl dodecanoate) is a fatty acid methyl ester. Methyl laurate can serve as a raw material to produce sucrose monolaurate via transesterification with sucrose .

HY-Y0271R

Urea (Standard) Carbonyl diamide (Standard)	Structural Classification Natürliche Produkte Microorganisms Endogenous metabolite Source Classification	Carbonic Anhydrase Reference Standards Endogenous Metabolite ERK Apoptosis
Urea (Standard) is the analytical standard of Urea. This product is intended for research and analytical applications. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-113972

Methyl mycophenolate	Monophenols Microorganisms Classification of Application Fields Marine natural products Phenols Inflammation/Immunology Disease Research Fields Marine microorganism	Others
Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae .

HY-N8064

Methyl cis-15-tetracosenoate methyl nervonate; methyl (Z)-tetracos-15-enoate; Nervonic acid methyl este	Structural Classification Lipid	Drug Derivative
Methyl cis-15-tetracosenoate (Methyl nervonate; Methyl (Z)-tetracos-15-enoate; Nervonic acid methyl ester) is the methyl ester form of nervonic acid (Nervonic acid, HY-N2526). Nervonic acid is an orally active monounsaturated fatty acid. Nervonic acid exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. Nervonic acid can be used in the research of neurodegenerative diseases .

HY-W009082R

Methyl behenate (Standard) methyl docosanoate (Standard)	Structural Classification Natürliche Produkte other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Reference Standards Biochemical Assay Reagents
Methyl behenate (Standard) is the analytical standard of Methyl behenate (HY-W009082). This product is intended for research and analytical applications. Methyl behenate (Methyl docosanoate) is a fatty acid methyl ester. Methyl behenate can be isolated from the plant Aspidopterys obcordata Lemsl. Methyl behenate can be used as a phase change material .

HY-107830R

Methyl cholate (Standard)	Structural Classification Microorganisms Steroids Source Classification	Reference Standards Endogenous Metabolite Collagen
Methyl cholate (Standard) is the analytical standard of Methyl cholate. This product is intended for research and analytical applications. Methyl cholate is a bile acid analog and a specific inhibitor of TcdB toxin from Clostridioides difficile. Methyl cholate exerts a stronger selective inhibitory effect on TcdB than on TcdA. Methyl cholate induces conformational stabilization by binding to a unique site of TcdB, thereby blocking the binding of the toxin to host receptors and its self-processing process. Methyl cholate effectively protects human fibroblasts from TcdB-induced cytopathic effects. Methyl cholate exhibits dose-dependent anti-hepatic fibrosis activity in both cellular and zebrafish models, and significantly reduces the expression levels of α-SMA and COL-I. Methyl cholate is suitable for in-depth research in the fields of Clostridioides difficile infection and hepatic fibrosis .

HY-W011688R

Methyl palmitoleate (Standard) (Z)-methyl hexadec-9-enoate (Standard); methyl cis-9-Hexadecenoate (Standard)	Structural Classification Natürliche Produkte other families Plants Source Classification	Reference Standards Drug Isomer
Methyl palmitoleate (Standard) is the analytical standard of Methyl palmitoleate. This product is intended for research and analytical applications. Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties .

HY-W960563

*C16-Urea-Ceramide*	Lipid	Biochemical Assay Reagents
C16-Urea-Ceramide is a bioactive ceramide.

Species:	Human (6) E.coli (1)
Tag:	His (5) Strep (1) Tag Free (1) Myc (1) GST (1) MBP (1) Flag (1)
Source:	HEK293 (1) Sf9 insect cells (2) E. coli (4)

Art. -Nr.	Compare	Produktname	Species	Source	Image

HY-P702009

	SLC14A1 Protein, Human (sf9, His, MBP, FLAG) SLC14A1; Urea transporter 1; Solute carrier family 14 member 1; Urea transporter; erythrocyte	Human	Sf9 insect cells
	SLC14A1 Protein plays a pivotal role in cellular processes, mediating urea transport across erythrocyte and renal inner medullary collecting duct membranes. It is crucial for the urinary concentrating mechanism and regulates water transport in erythrocytes. With a dual role in urea transport, SLC14A1 maintains cellular osmotic balance and contributes to physiological processes associated with urinary concentration, highlighting its significance. SLC14A1 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC14A1 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.

HY-P702948

	BCKDK Protein, Human (sf9, GST) Branched-chain alpha-ketoacid dehydrogenase kinase; BCKDH kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase; mitochondrial	Human	Sf9 insect cells
	BCKDK Protein, Human (sf9, GST) is the recombinant human-derived BCKDK, expressed by Sf9 insect cells , with GST labeled tag.

HY-P70366

	MeCP2 Protein, Human (HEK293, His) 1 Publications Verification rHumethyl-CpG-binding protein 2/MECP2, His; methyl-CpG-binding protein 2; MECP2; MeCp-2 protein	Human	HEK293
	The MeCP2 protein is a chromosome binder that specifically binds to methylated DNA independent of flanking sequences. MeCP2 Protein, Human (HEK293, His) is the recombinant human-derived MeCP2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P703609

	BCKDK Protein, Human Branched-chain alpha-ketoacid dehydrogenase kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; 2.7.11.4; BCKDK; Homo sapiens; Human; Kinase; Transferase; 2.7.11.1	Human	E. coli
	BCKDK Protein, Human is the recombinant human-derived BCKDK, expressed by E. coli, with tag free labeled tag.

HY-P703610

	BCKDK Protein, Human (His, Strep) Branched-chain alpha-ketoacid dehydrogenase kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; 2.7.11.4; BCKDK; Homo sapiens; Human; Kinase; Transferase; 2.7.11.1	Human	E. coli
	BCKDK Protein, Human (His, Strep) is the recombinant human-derived BCKDK, expressed by E. coli, with Strep, His labeled tag.

HY-P71457

	Dxr/DXP reductoisomerase Protein, E.coli (Myc, His) dxr; ispC; yaeM; b0173; JW01681-deoxy-D-xylulose 5-phosphate reductoisomerase; DXP reductoisomerase; EC 1.1.1.267; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase	E.coli	E. coli
	Dxr/DXP Reductoisomerase is pivotal in isoprenoid biosynthesis, catalyzing the rearrangement and reduction of DXP to yield MEP. This step is critical in forming isoprenoid precursors, essential for cellular processes and metabolite synthesis. The enzyme's activity emphasizes its significance in regulating isoprenoid biosynthesis and cellular functions. Dxr/DXP reductoisomerase Protein, E.coli (Myc, His) is the recombinant E. coli-derived Dxr/DXP reductoisomerase protein, expressed by E. coli , with C-Myc, N-10*His labeled tag.

HY-P701888

	FTO Protein, Human (His) FTO; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO	Human	E. coli
	FTO protein is an RNA demethylase that regulates fat mass, lipogenesis, and energy homeostasis by targeting N(6)-methyladenosine in mRNA. It also demethylates m6A in U6 snRNA and m6A(m) in 5'-cap, affecting mRNA stability. FTO Protein, Human (His) is the recombinant human-derived FTO protein, expressed by E. coli , with N-6*His labeled tag.

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Art. -Nr.	Produktname	Chemical Structure

HY-118877

Urea-13C 1 Publications Verification
Urea- ¹³C is the ¹³C labelled urea. The Urea- ¹³C breath test ( ¹³C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection .

HY-Y0271S1

Urea-d4
Urea-d₄ is the deuterium labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-23337S

*1-Methyl-3-((tetrahydrofuran-3-yl)methyl)urea-d3*
1-Methyl-3-((tetrahydrofuran-3-yl)methyl)urea-d₃ is the deuterium labeled γ-Tocotrienol. γ-Tocotrienol is an active form of vitamin E[1].

HY-W699637

*4-[[(4-Fluorophenyl)imino]methyl]phenol-d4*
4-[[(4-Fluorophenyl)imino]methyl]phenol-d₄ (4-{(E)-[(4-Fluorophenyl)imino]methyl}phenol-d₄) is the deuterium labeled 4-[[(4-Fluorophenyl)imino]methyl]phenol (HY-W014178).

HY-W751537

*4-[[(4-Fluorophenyl)imino]methyl]phenol-13C6*
4-[[(4-Fluorophenyl)imino]methyl]phenol- ¹³C₆ (4-{(E)-[(4-Fluorophenyl)imino]methyl}phenol- ¹³C₆) is the ¹³C-labeled 4-[[(4-Fluorophenyl)imino]methyl]phenol (HY-W014178).

HY-W714523

*1-Bis(4-fluorophenyl)methyl* Piperazine-d8**
1-Bis(4-fluorophenyl)methyl Piperazine-d₈ is the deuterium labeled 1-(Bis(4-fluorophenyl)methyl)piperazine (HY-W009293).

HY-W009293S

*1-(Bis(4-fluorophenyl)methyl)piperazine-d4*
1-(Bis(4-fluorophenyl)methyl)piperazine-d₄ (N-(4,4-Difluorobenzhydryl)piperazine-d₄) is the deuterium labeled 1-(Bis(4-fluorophenyl)methyl)piperazine.

HY-W699749

*Guanyl Urea* hydrochloride-15N4**
Guanyl Urea hydrochloride- ¹⁵N₄ is the ¹⁵N labeled Carbamoyl-guanidine Amidino Urea (HY-W738276).

HY-Z6285S

*N-Acetylethylene urea-d4*
N-Acetylethylene urea-d₄ is the deuterium labeled 1-Acetylimidazolidin-2-one (HY-W012753).

HY-42118S

4-(4-Fluorobenzylamino)-1-methylpiperidine-d2
4-(4-Fluorobenzylamino)-1-methylpiperidine-d₂ (N-[(4-Fluorophenyl)methyl]-1-methyl-4-piperidinamine-d₂) is the deuterium labeled 4-(4-Fluorobenzylamino)-1-methylpiperidine.

HY-W051189S

*(4-Fluorophenyl)methanol-d4*
(4-Fluorophenyl)methanol-d₄ is the deuterium labeled (4-Fluorophenyl)methanol .

HY-W024104S

*2-(4-Fluorophenyl)pyridine-d8*
2-(4-Fluorophenyl)pyridine-d8 is the deuterium labeled 2-(4-Fluorophenyl)pyridine (HY-W024104) .

HY-W707849

*3-(4-Fluorophenyl)-1-isopropyl-1H-indole-d7*
3-(4-Fluorophenyl)-1-isopropyl-1H-indole-d₇ is the deuterium labeled 3-(4-Fluorophenyl)-1-isopropyl-1H-indole (HY-W088000).

Host:	Mouse (4) Rabbit (21)
Reactivity:	Human (23) mouse (1) rat (1) Rat (17) Mouse (22) Monkey (1) Species independent (1)
Application:	WB IHC-P (1) IHC-P (16) ICC/IF (18) CHIP (4) IF-Tissue (1) IP (10) Cut&Tag (4) WB (23) ChIP (2) FC (3) ELISA (10)
Isotype:	IgG,Kappa (5) IgG (15) IgG1 (1) IgG/Kappa (1) IgG2a (1)
Conjugation:	Non-conjugated (25)
Clonality:	Monoclonal (23) Recombinant (16)
Modification:	Methylated (19) Unmodified (4)

Art. -Nr.	Compare	Produktname	Application	Reactivity	Image

HY-P86970

	*Mono-Methyl* Arginine (RGG) Antibody (YA6663)* Arginine (mono methyl) antibody; Mono-methyl Arginine (R*GG)	WB	Species independent
	Mono-Methyl Arginine (RGG) Antibody (YA6663) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mono-Methyl Arginine (RGG).

HY-P81950

	MBD3 Antibody (YA1695) MBD3; methyl-CpG-binding domain protein 3; methyl-CpG-binding protein MBD3	WB, ICC/IF, FC, IP	Human, Mouse, Rat
	MBD3 Antibody (YA1695) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MBD3.

HY-P87785

	*Histone H4 (Mono Methyl* Lys20) Antibody (YA7470)**	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	Histone H4 (Mono Methyl Lys20) Antibody (YA7470) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Histone H4 (Mono Methyl Lys20).

HY-P87842

	*Histone H4 (Tri Methyl* Lys20) Antibody (YA7527)**	WB, IHC-P, ICC/IF, IP, ELISA, CHIP, Cut&Tag	Human, Mouse, Rat
	Histone H4 (Tri Methyl Lys20) Antibody (YA7527) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Histone H4 (Tri Methyl Lys20).

HY-P80171

	*Histone H3 (di methyl* K9) Antibody (YA373)**	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	Histone H3 (di methyl K9) Antibody (YA373) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (di methyl K9).

HY-P80172

	*Histone H3 (mono methyl* K18) Antibody (YA372)**	WB, ICC/IF, IHC-P	Human, Mouse
	Histone H3 (mono methyl K18) Antibody (YA372) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (mono methyl K18).

HY-P80173

	*Histone H3 (mono methyl* K36)Antibody (YA371)**	WB, ICC/IF	Human, Mouse
	Histone H3 (mono methyl K36)Antibody (YA371) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (mono methyl K36).

HY-P80174

	*Histone H3 (mono methyl* R2)Antibody (YA370)**	WB, ICC/IF	Human, Mouse
	Histone H3 (mono methyl R2)Antibody (YA370) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (mono methyl R2).

HY-P80181

	*Histone H4 (tri methyl* K20) Antibody (YA364)**	WB, IHC-P	Human, Mouse
	Histone H4 (tri methyl K20) Antibody (YA364) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H4 (tri methyl K20).

HY-P87899

	*Histone H3 (Di Methyl* Lys27) Antibody (YA7584)**	WB, IHC-P, ICC/IF, IP, ELISA, CHIP, Cut&Tag	Human, Mouse, Rat
	Histone H3 (Di Methyl Lys27) Antibody (YA7584) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Histone H3 (Di Methyl Lys27).

HY-P87915

	*Histone H3 (Mono Methyl* Lys4) Antibody (YA7600)**	WB, IHC-P, ICC/IF, IP, ELISA, CHIP, Cut&Tag	Human, Mouse, Rat
	Histone H3 (Mono Methyl Lys4) Antibody (YA7600) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Histone H3 (Mono Methyl Lys4).

HY-P87930

	*Histone H3 (Tri Methyl* Lys4) Antibody (YA7615)**	WB, IHC-P, ICC/IF, IP, ELISA, CHIP, Cut&Tag	Human, Mouse, Rat
	Histone H3 (Tri Methyl Lys4) Antibody (YA7615) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Histone H3 (Tri Methyl Lys4).

HY-P80165

	*Histone H2B (mono methyl* R79) Antibody (YA376)**	WB, ICC/IF, IHC-P	Human, Mouse
	Histone H2B (mono methyl R79) Antibody (YA376) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2B (mono methyl R79).

HY-P80175

	*Histone H3 (mono+di+tri methyl* K79) Antibody (YA369)**	WB, IHC-P	Human, Mouse, Rat
	Histone H3 (mono+di+tri methyl K79) Antibody (YA369) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (mono+di+tri methyl K79).

HY-P86957

	MBD1 Antibody (YA6650) CXXC 3 antibody; CXXC-type zinc finger protein 3 antibody; CXXC3 antibody; MBD 1 antibody; Mbd1 antibody; MBD1_HUMAN antibody; MECP1 COMPLEX antibody; methyl CpG binding domain protein 1 antibody; methyl CpG binding domain protein 1 isoform PCM1 antibody; methyl CpG binding protein MBD1 antibody; CXXC 3 antibody; CXXC-type zinc finger protein 3 antibody; CXXC3 antibody; MBD 1 antibody; Mbd1 antibody; MBD1_HUMAN antibody; MECP1 COMPLEX antibody; methyl CpG binding domain protein 1 antibody; methyl CpG binding domain protein 1 isoform PCM1 antibody; methyl CpG binding protein MBD1 antibody; methyl CpG binding protein splice variant 1 antibody; methyl CpG binding protein splice variant 2 antibody; methyl CpG binding protein splice variant 3 antibody; methyl CpG binding protein splice variant 4 antibody; methyl-CpG-binding domain protein 1 antibody; methyl-CpG-binding protein MBD1 antibody; PCM 1 antibody; PCM1 antibody; Protein containing methyl-CpG-binding domain 1 antibody; Regulator of fibroblast growth factor 2 (FGF 2) transcription antibody; RFT antibody; The regulator of fibroblast growth factor 2(FGF 2) transcription antibody;	WB, ICC/IF, FC	Mouse, Rat
	MBD1 Antibody (YA6650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MBD1.

HY-P86190

	MECP2 Antibody (YA5882) methyl-CpG-binding protein 2; MeCp-2 protein; MeCp2;	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	MECP2 Antibody (YA5882) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MECP2.

HY-P810471

	BCKDK Antibody BCKDK, Branched Chain Keto Acid Dehydrogenase Kinase, [3-methyl-2-Oxobutanoate Dehydrogenase [Lipoamide]] Kinase, Mitochondrial, Branched-Chain Alpha-Ketoacid Dehydrogenase Kinase, BCKDH Kinase, EC 2.7.11.4, BCKDHKIN, BDK, 3-methyl-2-Oxobutanoate Dehydrogenase [Lipoamide] Kinase, Mitochondrial, Branched Chain Alpha-Ketoacid Dehydrogenase Kinase, Branched Chain Ketoacid Dehydrogenase Kinase, BCKD-Kinase, EC 2.7.11.1, EC 2.7.11, BCKDKD	WB IHC-P	Human, mouse, rat
	BCKDK Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to BCKDK.

HY-P87443A

	NR3B/GRIN3B Antibody (YA7131)(PBS only) GluN3B, N-methyl-D-aspartate receptor subtype 3B, NMDAR3B, NR3B, GRIN3B	FC, ELISA	Human
	NR3B/GRIN3B Antibody (YA7131) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NR3B/GRIN3B.

HY-P87363

	*Histone H3 (mono+di+tri methyl* K79) Antibody (YA7046)** H3 histone family member E pseudogene antibody; H3 histone family, member A antibody; H3/A antibody; H31_HUMAN antibody; H3F3 antibody; H3FA antibody; Hist1h3a antibody; HIST1H3B antibody; HIST1H3C antibody; HIST1H3D antibody	WB, IHC-P, ICC/IF, ChIP	Human, Mouse, Rat, Monkey
	Histone H3 (mono+di+tri methyl K79) Antibody (YA7046) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (mono+di+tri methyl K79).

HY-P80176

	*Histone H3 (tri methyl* K9) Antibody (YA734)** H3K9me3; H3 histone family member E pseudogene; H3 histone family, memberA; H3/A; H31_HUMAN; H3F3; H3FA; Hist1h3a; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST3H3; histone 1, H3a; Histone cluster 1, H3a; Histone H3 3 pseudogene; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; HistoneH3/l; H3K9me2; HistoneH3(trimethylK9)	WB, IHC-P, ICC/IF, IF-Tissue	Human, Mouse, Rat
	Histone H3 (tri methyl K9) Antibody (YA734) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Histone H3 (tri methyl K9).

HY-P86113

	*Histone H3 (Di Methyl* Lys4) Antibody (YA5805)** H3K4ME2; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3.1; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3; H3F3C; Histone H3.3C; Histone H3.5	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Histone H3 (Di Methyl Lys4) Antibody (YA5805) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (Di Methyl Lys4).

HY-P85671

	*Histone H3 (Tri Methyl* Lys36) Antibody (YA5363)** H3K36ME3; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3	WB, IP	Human, Mouse, Rat
	Histone H3 (Tri Methyl Lys36) Antibody (YA5363) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Histone H3 (Tri Methyl Lys36).

HY-P86148

	*Histone H3 (Di Methyl* Lys9) Antibody (YA5840)** H3K9ME2; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3	WB, IHC-P, ICC/IF, IP, ChIP, ELISA	Human, Mouse, Rat
	Histone H3 (Di Methyl Lys9) Antibody (YA5840) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (Di Methyl Lys9).

HY-P85670

	*Histone H3 (Di Methyl* Lys79) Antibody (YA5362)** H3K79ME2; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3	WB	Human, Mouse, Rat
	Histone H3 (Di Methyl Lys79) Antibody (YA5362) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Histone H3 (Di Methyl Lys79).

HY-P86071

	*Histone H3 (Tri Methyl* Lys36) Antibody (YA5763)** H3K36ME3; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Histone H3 (Tri Methyl Lys36) Antibody (YA5763) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (Tri Methyl Lys36).

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Art. -Nr.	Produktname		Classification

HY-152684

*2′-O-2-Propyn-1-ylguanosine*		Alkynes
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154338

*N-Benzoyl-2′-O-2-propyn-1-yladenosine*		Alkynes
N-Benzoyl-2′-O-2-propyn-1-yladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) . N-Benzoyl-2′-O-2-propyn-1-yladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-128930

*6-O-2-Propyn-1-yl-D-galactose*		Alkynes ADC Synthesis
6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic agents and applications in antibody-agent conjugation. 6-O-2-Propyn-1-yl-D-galactose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-177696

*3-[4-(2-Propyn-1-yloxy)phenyl]-2H-azirine*		Alkynes
3-[4-(2-Propyn-1-yloxy)phenyl]-2H-azirine (Compound AZ-9) is a reactive probe based on 3-phenyl-2H-azirine, enabling chemoselective bioconjugation of carboxyl residues in proteins with excellent labeling efficiency and specificity under both in vitro and in situ conditions in live cells .

Art. -Nr.	Produktname		Classification

HY-152684

*2′-O-2-Propyn-1-ylguanosine*		Nucleoside Analogs Guanosine
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154338

*N-Benzoyl-2′-O-2-propyn-1-yladenosine*		Nucleoside Analogs Adenosine
N-Benzoyl-2′-O-2-propyn-1-yladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) . N-Benzoyl-2′-O-2-propyn-1-yladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154733

*9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine*		Nucleoside Analogs
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152580

*5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine*		Nucleoside Analogs Uridine
5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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